*abcdefghijklmnopqrstuvwxyz
Rare generalized ichthyosis associated with mental retardation and progressive spastic di- or tetraplegia. Retinal changes, dental and skeletal deformities have been present in many cases. Fatty alcohol oxidoreductase deficiency plays a major role in the pathogenesis of this disease. The disorder is inherited as an autosomal recessive trait.
Sjögren-Larsson Syndrome