A chronic, localized hardening and thickening of the skin. Lesions may be categorized as morphea (guttate, profunda, pansclerotic) or linear (with or without melorheostosis or hemiatrophy). It is twice as common in women as in men. The condition is characterized by skin ischaemia, lymphocytic infiltrates, swollen collagen bundles, and thickening of the dermis with reduction of subcutaneous fat.
Localized Scleroderma, Circumscribed Scleroderma, Morphea
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