Symmetric bluish discolouration or the hands and feet that is variable in intensity and more pronounced in hypothermia. The peripheral arterioles react unduly to cold and the smaller vessels are dilated. The disorder is not usually associated with gross arterial disease. In new-borns acrocyanosis is a physiologic finding. If it starts later, most commonly in adolescence, acrocyanosis may either persist or improve in adult life. The bluish-red discolouration may occur transiently after exposure to cold, or be persistent through the winter or even the summer months.
Acrocyanosis, CASSIRER SYNDROME, CROCQ DISEASE, Crocq's disease, Disease, Crocq's
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