Henoch-Schonlein Purpura is an immunologically mediated, usually self-limited vasculitis of the small blood vessels of the skin. It is the most common form of childhood vasculitis and results in inflammatory changes in the small blood vessels. The symptoms of Henoch-Schonlein Purpura usually begin suddenly and may include headache, fever, loss of appetite, cramping abdominal pain, and joint pain. Red or purple spots typically appear on the skin (petechial purpura). Inflammatory changes associated with Henoch-Schonlein Purpura can also develop in the joints, kidneys, digestive system, and, in rare cases, the brain and spinal cord. In one form of the disorder, termed Schonlein's Purpura, the skin and joints are affected but the gastrointestinal tract is not. In another form, known as Henoch's Purpura, affected individuals have purpuric spots on the skin and acute abdominal problems but are not affected by joint pain. The exact cause of Schonlein-Henoch Purpura is not fully understood, although research suggests that it may be an autoimmune disease or, in some rare cases, an extreme allergic reaction to certain offending substances (e.g., foods or drugs).
Purpura Rheumatica, Schönlein-Henoch Purpura
Peliosis rheumatica, Purpura rheumatica
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